Effects of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition on resistance artery tone in patients with end stage kidney disease.

Julia Steinmetz-SpähSamsul ArefinKarin LarssonJabin JahanNeja MudrovcicLars WennbergPeter StenvinkelMarina KorotkovaKarolina KublickienePer-Johan Jakobsson

Published in: British journal of pharmacology (2021)

Our study demonstrates vasodilating effects following mPGES-1 inhibition in human microvasculature and suggests that several pathways besides shunting to PGI2 may be involved.

Keyphrases

endothelial cells
pluripotent stem cells