The relationship between myocardial microstructure and strain in chronic infarction using cardiovascular magnetic resonance diffusion tensor imaging and feature tracking.
N SharrackA DasC KellyI TehC T StoeckS KozerkeP P SwobodaJ P GreenwoodS PleinJ E SchneiderErica Dall'ArmellinaPublished in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2022)
Change in sheetlet orientation assessed using E2A from cDTI correlates with impaired radial strain. Segments with fewer subendocardial cardiomyocytes, evidenced by a lower proportion of myocytes with right-handed orientation on HA maps, show impaired longitudinal strain. Infarct segment enhancement correlates significantly with E2A and RHM. Our data has demonstrated a link between myocardial microstructure and contractility following myocardial infarction, suggesting a potential role for CMR cDTI to clinically relevant functional impact.
Keyphrases
- magnetic resonance
- left ventricular
- white matter
- heart failure
- acute myocardial infarction
- machine learning
- deep learning
- electronic health record
- multiple sclerosis
- big data
- magnetic resonance imaging
- cross sectional
- coronary artery disease
- smooth muscle
- atrial fibrillation
- acute coronary syndrome
- endothelial cells
- contrast enhanced
- drug induced