Ethanol-mediated suppression of IL-37 licenses alcoholic liver disease.
Felix GrabherrChristoph GranderTimon E AdolphVerena WieserLisa MayrBarbara EnrichSophie MacheinerMoris SanginetoAndreas ReiterAndre ViveirosHeinz ZollerPhilip BuflerAlexander R MoschenCharles A DinarelloHerbert TilgPublished in: Liver international : official journal of the International Association for the Study of the Liver (2017)
We provide evidence for an exogenous noxae that suppresses Interleukin 37 expression which limits its anti-inflammatory effects in alcoholic liver disease.