The Efficacy of Intense Pulsed Light in the Treatment of Keloids and Hypertrophic Scars.
Le Thai Van ThanhTran So QuanLe Vi AnhTa Quoc HungNguyen Lam VuongPublished in: Journal of lasers in medical sciences (2023)
Introduction: Different therapies have been applied to keloids and hypertrophic scars. Intense pulsed light (IPL) has recently been used but the evidence is limited. This study was to evaluate the effectiveness and safety of IPL as monotherapy for keloids and hypertrophic scars. Methods: This was a before-and-after interventional study on 16 patients with 50 scars who underwent IPL. Seven scars receive one IPL session, seven received two sessions, and 36 received three sessions. Outcomes were evaluated by the Vancouver Scar Scale (VSS), Patient and Observer Scar Assessment Scale (POSAS), scar ultrasound, colorimeter for pigmentation and erythema, and side effects. Results: After the treatment, most outcomes significantly improved except that the pigmentation of the scars did not change. Scar thickness significantly reduced by nearly 10% after the first IPL session, 15% after the second session, and>20% after the third session. All side effects were mild with crust (33.3-46%), blisters (8.3-40%), and hyperpigmentation around the scar (0-14%); the pain was moderate as assessed by the patients. Conclusion: IPL is a safe and effective treatment for keloids and hypertrophic scars. More studies are required to confirm our results.
Keyphrases
- platelet rich plasma
- high intensity
- combination therapy
- end stage renal disease
- wound healing
- randomized controlled trial
- magnetic resonance imaging
- chronic pain
- ejection fraction
- metabolic syndrome
- case report
- adipose tissue
- open label
- pain management
- spinal cord injury
- optical coherence tomography
- peritoneal dialysis
- patient reported outcomes
- study protocol
- smoking cessation