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Intraarterial Nimodipine Versus Induced Hypertension for Delayed Cerebral Ischemia: A Modified Treatment Protocol.

Miriam WeissWalid AlbannaCatharina Conzen-DilgerNick KastenholzKatharina SeyfriedHani RidwanMartin WiesmannMichael VeldemanTobias Philip SchmidtMurad MegjhaniHenna Schulze-SteinenHans ClusmannMarinus Johannes Hermanus AriesSoojin ParkGerrit Alexander Schubert
Published in: Stroke (2022)
Assuming the potential of iHTN to be exhausted in case of refractory hypoperfusion, additional IAN may serve as a last-resort measure to bridge hypoperfusion in the DCI phase. With close monitoring, preemptive lowering of pressure target after induction of IAN may be a safe alternative to alleviate total noradrenaline load and potentially reduce complication rate.
Keyphrases
  • cerebral ischemia
  • subarachnoid hemorrhage
  • cognitive impairment
  • brain injury
  • blood pressure
  • blood brain barrier
  • randomized controlled trial
  • drug induced
  • risk assessment
  • climate change