Instrumental variables in real-world clinical studies of dementia and neurodegenerative disease: Systematic review of the subject-matter argumentation, falsification test, and study design strategies to justify a valid instrument.
Shaun Kuan Wei HiuTingting YongJahfer HasoonM Dawn TeareJohn-Paul TaylorNan LinPublished in: Brain and behavior (2024)
Our results reinforce IV analysis as a feasible option for clinical researchers in dementia and neurodegenerative disease by clarifying known strategies used to validate an IV.