Using Machine Learning Algorithms to Predict Immunotherapy Response in Patients with Advanced Melanoma.
Paul JohannetNicolas CoudrayDouglas M DonnellyGeorge JourIrineu Illa-BochacaYuhe XiaDouglas B JohnsonLee WhelessJames Randall PatrinleySofia NomikouDavid L RimmAnna C PavlickJeffrey S WeberJudy ZhongAristotelis TsirigosIman OsmanPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Histology slides and patients' clinicodemographic characteristics are readily available through standard of care and have the potential to predict ICI treatment outcomes. With prospective validation, we believe our approach has potential for integration into clinical practice.