Fast versus ultra-slow thrombolytic infusion regimens in patients with obstructive mechanical prosthetic valve thrombosis: a pilot randomized clinical trial.

Parham Sadeghipour Sedigheh Saedi Leila Saneei Farnaz Rafiee Siamak Yoosefi Mozhgan Parsaee Rashide Siami Milad Saberi Hamidreza Pouraliakbar Behshid Ghadrdoost Hooman Bakhshande Mohammad Mehdi Peighambari Melody Farrashi Bahram Mohebbi Ahmad Amin Ahmad AminMajid MalekiZahra Khajali Raffaele De Caterina

Published in: European heart journal. Cardiovascular pharmacotherapy (2021)

The ultraslow thrombolytic regimen conferred a high thrombosis resolution rate without major complications. Such findings should be replicated in more adequately powered trials (IRCT20181022041406N2).

Keyphrases

pulmonary embolism
aortic valve
mitral valve
low dose
high resolution
acute ischemic stroke
risk factors
study protocol
aortic stenosis
double blind
randomized controlled trial
transcatheter aortic valve replacement
ejection fraction