It is possible to use the FHIR standard and an open-source information model represented in our IG to build an open, interoperable clinical trial register. Advanced features like user suggestions and audit trails of individual resource fields could be represented by extending the FHIR standard. CATS is the first implementation of an open-for-collaboration clinical trial registry with modern oncological trial designs and machine-to-machine communication in mind and its methodology could be extended to other medical fields besides precision oncology. Due to its well-defined interfaces, it has the potential to provide automated patient recruitment decision support for precision oncology trials in digital applications.
Keyphrases
- clinical trial
- phase ii
- healthcare
- palliative care
- phase iii
- deep learning
- study protocol
- open label
- primary care
- double blind
- quality improvement
- health information
- mental health
- machine learning
- case report
- high throughput
- prostate cancer
- randomized controlled trial
- radical prostatectomy
- robot assisted
- climate change
- placebo controlled
- minimally invasive