In pursuit of biomarkers for predicting susceptibility to activity-based anorexia in adolescent female rats.
Laura Karina MiltonTimothy PattonMeredith O'KeeffeBrian John OldfieldClaire Jennifer FoldiPublished in: The International journal of eating disorders (2022)
Anorexia nervosa (AN) has among the highest mortality rates of all psychiatric disorders and treatment options remain limited in their efficacy. Understanding what types of risk factors contribute to the development of AN is essential for implementing early intervention strategies. This study describes how some of the most common psychological features of AN could be used to predict susceptibility to pathological weight loss in a well-established animal model.