Exosomal CagA from Helicobacter pylori aggravates intestinal epithelium barrier dysfunction in chronic colitis by facilitating Claudin-2 expression.

Yinjie GuoCanxia XuRenjie GongTingzi HuXue ZhangXiaoran XieJingshu ChiHuan LiXiujuan XiaXiao-Ming Liu

Published in: Gut pathogens (2022)

H. pylori infection are indispensable for damaging the mucosal barrier integrity in chronic colitis, which may provide a new idea for inflammatory bowel disease (IBD) treatment.

Keyphrases

helicobacter pylori
ulcerative colitis
helicobacter pylori infection
poor prognosis
oxidative stress
drug induced
combination therapy
binding protein
long non coding rna