A dual MTOR/NAD+ acting gerotherapy.
Jinmei LiSandeep KumarKirill MiachinNicholas L BeanOrnella HalawiScott M LeeJiWoong ParkTanya H PierreJin-Hui HorShi Yan NgKelvin J WallaceNiklas RindtorffTimothy M MillerMichael L NiehoffSusan A FarrRolf F KletzienJerry R ColcaSteven P TanisYana ChenKristine GriffettKyle S McCommisBrian N FinckTimothy R PetersonPublished in: bioRxiv : the preprint server for biology (2023)
These studies characterize a novel gerotherapy, BIOIO-1001, that identifies lipid metabolism as an intersection of the mTOR and NAD+ pathways.