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Diffuse alveolar haemorrhage in children: an international multicentre study.

Astrid Madsen RingNicolaus SchwerkNural KiperAyse Tana AslanPaul AuroraRoser AyatsInes AzevedoTeresa BandeiraJulia CarlensSilvia Castillo-CorullonFatma Nazan ÇobanoğluBasil ElnazirNagehan EmiralioğluTugba Sismanlar EyubogluMichael FayonTugba Ramaslı GursoyClaire HoggKarsten KötzBülent Taner KaradağVendula LátalováKatarzyna KrenkeJoanna LangeEffrosyni D ManaliBorja Osona Rodriguez de TorresSpyros PapirisMarijke ProesmannPhilippe ReixLea RoditisSune RubakNisreen RummanDeborah SnijdersFlorian StehlingLaurence WeissEbru YalcınFazilcan ZirekAndrew BushAnnick ClementMatthias GrieseFrederik Fouirnaies BuchvaldNadia NathanKim Gjerum Nielsen
Published in: ERJ open research (2023)
Paediatric DAH is highly heterogeneous regarding underlying causes and clinical presentation. The high mortality rate and number of patients with ongoing treatment years after onset of disease underline that DAH is a severe and often chronic condition. This large international study paves the way for further prospective clinical trials that will in the long term allow evidence-based treatment and follow-up recommendations to be determined.
Keyphrases
  • clinical trial
  • emergency department
  • young adults
  • randomized controlled trial
  • cardiovascular events
  • intensive care unit
  • replacement therapy
  • combination therapy
  • phase ii