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Population/regional differences in efficacy of 3 drug categories (antidiabetic, respiratory and psychotropic agents) among East Asians: A retrospective study based on multiregional clinical trials.

Kimie SaiAkiomi YoshidaTadaaki HanataniTakuya ImatohMasahiro TakeuchiMamoru NarukawaHiroshi WatanabeYoshiaki UyamaYoshiro Saito
Published in: British journal of clinical pharmacology (2019)
This study suggests that the regional variability in efficacy of these 3 drug categories is not large among East Asians, and reveals the importance of considering background factors when planning MRCTs. Further studies are needed to evaluate regional variability in the efficacy of other drug categories and clarify the factors leading to regional differences in East Asians.
Keyphrases
  • clinical trial
  • randomized controlled trial
  • emergency department
  • electronic health record
  • case control
  • double blind
  • respiratory tract