Maternal psychological distress during the COVID-19 pandemic and structural changes of the human fetal brain.
Yuan-Chiao LuNickie AndescavageYao WuKushal KapseNicole R AndersenJessica QuistorffHaleema SaeedCatherine LopezDiedtra HendersonScott D BarnettGilbert VezinaDavid WesselAdre du PlessisCatherine LimperopoulosPublished in: Communications medicine (2022)
We report impaired fetal brain growth and delayed cerebral cortical gyrification in COVID-19 pandemic era pregnancies, in the setting of heightened maternal psychological distress. The potential long-term neurodevelopmental consequences of altered fetal brain development in COVID-era pregnancies merit further study.
Keyphrases
- resting state
- pregnancy outcomes
- white matter
- cerebral ischemia
- functional connectivity
- birth weight
- endothelial cells
- preterm birth
- coronavirus disease
- gestational age
- sars cov
- sleep quality
- climate change
- body mass index
- brain injury
- blood brain barrier
- depressive symptoms
- pluripotent stem cells
- respiratory syndrome coronavirus