Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions.

Hannah BritzNina HankeMitchell E TaubTing WangBhagwat PrasadÉric FernandezPeter StopferValerie NockThorsten Lehr

Published in: Pharmaceutical research (2020)

Whole-body PBPK models of probenecid and furosemide were built and evaluated, providing useful tools to support the investigation of transporter mediated DDIs.

Keyphrases

emergency department