First-trimester cystic posterior fossa: reference ranges, associated findings, and pregnancy outcomes.
Raquel Garcia RodriguezRaquel García DelgadoAzahar Romero-RequejoMargarita Medina-CastellanoJose Angel Garcia-HernandezJesus Maria Gonzalez-MartinWaldo SepulvedaPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2019)
The detection of a CPF in the first trimester is associated with a high rate of chromosomal and structural defects. By using normative data, early sonographic screening and detection of mildly and moderately abnormal cases is possible. Fetuses with isolated CPF require further study with a detailed second-trimester scan. This is essential in order to differentiate cases with poor and good perinatal outcomes. Finally, our data also demonstrate that the main sonographic tool when screening for CPF in the first trimester is the assessment of the fourth ventricle, which is significantly larger in abnormal cases as the result of the wide communication between the fourth ventricle and the cisterna magna.
Keyphrases
- pregnancy outcomes
- genome editing
- pregnant women
- crispr cas
- electronic health record
- pulmonary artery
- pulmonary hypertension
- loop mediated isothermal amplification
- label free
- computed tomography
- real time pcr
- gestational age
- metabolic syndrome
- coronary artery
- optic nerve
- type diabetes
- magnetic resonance imaging
- pulmonary arterial hypertension
- copy number
- adipose tissue
- data analysis
- left ventricular
- genome wide
- dual energy