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HEV-3 subtypes and strains detected in cases of HEV infection in central Italy from 2015 to 2023.

Anna Rosa GarbugliaGjergji KojaUmbertina VillanoClaudia MinosseMichele EquestreSilvia PauciulloAntonio CoppolaElisabetta MadonnaGiovanna PicchiJessica Di BiaseMargherita DalessandroAnna RughettiKatia CasinelliBarbara CamilloniRinalda MarianiAlessandro GrimaldiAnna Rita CiccaglioneRoberto Bruni
Published in: Infection (2024)
The data provide an overview of the HEV strains responsible for human infections over eight years in Central Italy. The observed subtype distribution appears to agree better with the subtype distribution reported in Italy in pigs rather than in geographically matched wild boars, suggesting pig and its derivate food was a more frequent source of infection than wild boar in Abruzzo and Lazio. Molecular characterization is essential to recognize "point source outbreaks" and to monitor HEV circulation.
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