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A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences.

Emily R HildebrandtAnushka SarkarRajani RavishankarJune H KimWalter K Schmidt
Published in: bioRxiv : the preprint server for biology (2023)
We report yeast engineered to express human prenylation enzymes with which prenylation can be investigated for established and novel CaaX sequences associated with proteins involved in human disease.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • mass spectrometry
  • saccharomyces cerevisiae
  • small molecule
  • cell wall
  • atomic force microscopy