Genistein suppresses the inflammation and GSK-3 pathway in an animal model of spontaneous ovarian cancer

Füsun Erten Engin Yenice Cemal Orhan Besir Er Pinar Oner Patrick Brice Defo Deeh Kazım Şahin

Published in: Turkish journal of medical sciences (2021)

Genistein exhibited an anticancer effect by reducing proinflammatory biomarkers levels and inhibiting GSK-3 expression in the ovaries of old laying hens. It is a potential candidate in the chemoprevention and/or treatment of ovarian cancer.

Keyphrases

signaling pathway
pi k akt
heat stress
poor prognosis
oxidative stress
risk assessment
combination therapy
cell proliferation