The effect of a high-polyphenol Mediterranean diet (Green-MED) combined with physical activity on age-related brain atrophy: the Dietary Intervention Randomized Controlled Trial Polyphenols Unprocessed Study (DIRECT PLUS).
Alon KaplanHila ZelichaAnat Yaskolka MeirEhud RinottGal TsabanGidon LevakovOfer PragerMoti SaltiYoram YovellJonathan OferSebastian HuhnFrauke BeyerVeronica WitteArno VillringerNachshon MeiranTamar B EmeshPeter KovacsMartin von BergenUta CeglarekMatthias BlüherMichael StumvollFrank B HuMeir J StampferAlon FriedmanIlan ShelefGalia AvidanIris ShaiPublished in: The American journal of clinical nutrition (2022)
A Green-MED (high-polyphenol) diet, rich in Mankai, green tea, and walnuts and low in red/processed meat, is potentially neuroprotective for age-related brain atrophy.This trial was registered at clinicaltrials.gov as NCT03020186.