Therapeutic Effect of Polaprezinc on Reflux Esophagitis in the Rat Model.

Wenbo XieLu AnZhaoyang LiuXindi WangXueqi FuJunfeng Ma

Published in: Digestive diseases and sciences (2023)

Polaprezinc has a significant therapeutic effect on RE in rats, which can reduce the levels of IL-8 and PGE2 and downregulate the expression of PI3K/Akt/mTOR signal pathway protein. The efficacy of polaprezinc in the treatment of reflux esophagitis is comparable to that of PPI, and the combination of them is more effective in the reflux esophagitis treatment.

Keyphrases

poor prognosis
combination therapy
protein protein
amino acid
replacement therapy