Systematic review with meta-analysis: lubiprostone efficacy on the treatment of patients with constipation.

Maria do Carmo Friche Passos Maira Libertad Soligo Takemoto Gabriel Cyrillo Corradino Luciana S Guedes

Published in: Arquivos de gastroenterologia (2021)

Our findings demonstrated that lubiprostone is superior to placebo in terms of SBM frequency for CIC, IBS-C and OIC. In terms of abdominal symptoms, the most pronounced effect was seen for abdominal pain in IBS-C patients.

Keyphrases

abdominal pain
irritable bowel syndrome
end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
randomized controlled trial
patient reported outcomes
physical activity
combination therapy
sleep quality
smoking cessation