Scoping and targeted reviews to support development of SPIRIT and CONSORT extensions for randomised controlled trials with surrogate primary endpoints: protocol.

Anthony Muchai ManyaraPhilippa DaviesDerek StewartValerie WellsChristopher J Weir Amber E YoungRod TaylorOriana Ciani

Published in: BMJ open (2022)

Ethical approval is not required. The reviews will support the development of SPIRIT and CONSORT extensions for reporting surrogate primary endpoints (surrogate endpoint as the primary outcome). The findings will be published in open-access publications.This review has been prospectively registered in the OSF Registration DOI: 10.17605/OSF.IO/WP3QH.

Keyphrases

randomized controlled trial
minimally invasive
meta analyses
systematic review
cancer therapy
drug delivery
decision making
electronic health record
drug administration
cone beam