Prediction of sorafenib treatment-related gene expression for hepatocellular carcinoma: preoperative MRI and histopathological correlation.

Zhi DongKun HuangBing LiaoHuasong CaiYu DongMengqi HuangXiaoqi ZhouYingmei JiaLing XuYanji LuoZi-Ping LiShi Ting Feng

Published in: European radiology (2018)

• Incomplete tumor capsule and non-capsule were independent risk factors of HCC with high BRAF and RAF1 expression. • The presence of intratumoral vessels was a potential indicator of high BRAF and RAF1 expression. • Gadoxetic acid-enhanced MRI may be a predictor of efficacy of treatment with sorafenib.

Keyphrases

gene expression
risk factors
poor prognosis
magnetic resonance imaging
contrast enhanced
diffusion weighted imaging
computed tomography
binding protein
climate change
wild type