COVID-19 in hospitalized adult patients with sickle cell disease: A 2020 US cohort using Cerner Real-World Data ™ (CRWD).
Stephanie Howe GuarinoKimberly D WilliamsRichard J CaplanMitch FawcettSophie LanzkronPublished in: Journal of clinical and translational science (2023)
We used Cerner Real-World Data™, representing hospital admission records from 2020, to examine patients with co-occurring sickle cell disease and COVID-19 by discharge disposition grouped as death/hospice versus transfers to other facilities, returned home, or left against medical advice. Among the death/hospice group, we found older age and higher rates of congestive heart failure and diabetes. There were also significant differences in tachypnea, mechanical ventilation, minimum O 2 saturation, and length of stay with higher rates in the death/hospice group. Awareness of such factors and associated mortality risks for this population may aid in patient care.
Keyphrases
- sickle cell disease
- palliative care
- mechanical ventilation
- coronavirus disease
- sars cov
- heart failure
- healthcare
- advanced cancer
- electronic health record
- acute respiratory distress syndrome
- intensive care unit
- type diabetes
- cardiovascular disease
- big data
- emergency department
- physical activity
- respiratory failure
- adipose tissue
- cardiovascular events
- human health
- middle aged
- data analysis
- respiratory syndrome coronavirus
- acute care
- insulin resistance
- metabolic syndrome
- coronary artery disease
- acute heart failure