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Metal-Free Difluoromethylselenolation of Arylamines Under Visible-Light Photocatalysis.

Kui LuQuan LiXiaolan XiTing ZhouXia Zhao
Published in: The Journal of organic chemistry (2019)
A novel visible-light photocatalytic difluoromethylselenolation of aryl amines via in situ generation of aryldiazonium salts was achieved using Se-(difluoromethyl) 4-methylbenzenesulfonoselenoate, which was synthesized for the first time. The reagent is readily accessible and shelf-stable. The metal-free reaction conditions and the broad substrate scope provide a green protocol for the efficient and rapid introduction of the difluoromethylselenylether group.
Keyphrases
  • visible light
  • randomized controlled trial
  • ionic liquid
  • loop mediated isothermal amplification