Multiple sclerosis in patients with hereditary spastic paraplegia: a case report and systematic review.
Maria Pia GiannoccaroEleonora MatteoFiorina BartiromoCaterina TononFilippo M SantorelliRocco LiguoriGiovanni RizzoPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)
This is the first description on the association between SPG3A type of HSP and MS. This report adds to the other reported cases of co-occurring HSPs and MS. Although it remains unclear if this association is casual or causal, clinicians should be aware that an HSP diagnosis does not always exclude a concomitant MS.