The Impact of Immune-Modifying Treatments for Skin Diseases on the Immune Response to COVID-19 Vaccines: a Narrative Review.

Su-Yi Liew Timothy I M Tree Catherine H Smith Satveer K Mahil

Published in: Current dermatology reports (2022)

Inadequate humoral immune responses to a single dose of vaccine in the context of immune-modifying therapy are improved by a complete course of vaccination. Individuals receiving immune-modifying treatments should be encouraged to take up a complete vaccine course to mitigate their risk against COVID-19. Research in large patient populations on the longevity/kinetics of the complex humoral and cellular response to subsequent vaccine doses, including against newer variants of concern, is warranted, in addition to data on immune correlates of vaccine clinical effectiveness.

Keyphrases

immune response
coronavirus disease
sars cov
dendritic cells
randomized controlled trial
systematic review
case report
gene expression
stem cells
electronic health record
copy number
respiratory syndrome coronavirus
deep learning
cell therapy
data analysis
soft tissue
genetic diversity