Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalitis Following COVID-19: Systematic Review and Meta-synthesis.
Giovanna S ManzanoCaleb R S McEntireMaria Martinez-LageFarrah J MateenSpencer Kristian HuttoPublished in: Neurology(R) neuroimmunology & neuroinflammation (2021)
In contrast to ADEM cases from the prepandemic era, reported post-COVID-19 ADEM and AHLE cases were often advanced in age at onset, experienced severe antecedent infection, displayed an unusually high rate of hemorrhage on neuroimaging, and routinely had poor neurologic outcomes, including a high mortality rate. Findings are limited by nonstandardized reporting of cases, truncated follow-up information, and presumed publication bias.
Keyphrases
- systematic review
- coronavirus disease
- liver failure
- sars cov
- respiratory failure
- drug induced
- magnetic resonance
- meta analyses
- aortic dissection
- cardiovascular events
- randomized controlled trial
- early onset
- type diabetes
- risk factors
- emergency department
- extracorporeal membrane oxygenation
- adipose tissue
- health information
- intensive care unit
- metabolic syndrome
- skeletal muscle
- contrast enhanced
- acute respiratory distress syndrome