Advances of Light/Ultrasound/Magnetic-Responsive Nanoprobes for Visualized Theranostics of Urinary Tumors.
Fan YangShaowen LiMeng JiaoDi WuLuna WangZhenyu CuiLeyong ZengPublished in: ACS applied bio materials (2022)
Light/ultrasound/magnetic-responsive nanomaterials exhibit excellent performance in imaging and therapy and play an important role in precision theranostics of tumors. In contrast to deep organs, urinary organs (such as bladder and prostate) can easily be studied via intervention mode, which has greatly brought promising applications of stimuli-responsive nanoprobes in visualized theranostics of urinary tumors. Therefore, it has been very critical to develop stimuli-responsive nanoprobes with high safety, stability, and reliability against urinary tumors. In this review, recent advances in light/ultrasound/magnetic-responsive nanoprobes in visualized theranostics of urinary tumors are summarized, including magnetic resonance/fluorescence/ultrasound/photoacoustic imaging and multimodal imaging, photothermal/photodynamic/sonodynamic therapy and combination therapy, and single-modal/multimodal-imaging-guided visualized theranostics. Finally, the future perspectives of light/ultrasound/magnetic-responsive nanoprobes against urinary tumors are also prospected.
Keyphrases
- cancer therapy
- fluorescence imaging
- magnetic resonance
- magnetic resonance imaging
- high resolution
- combination therapy
- photodynamic therapy
- prostate cancer
- drug delivery
- molecularly imprinted
- randomized controlled trial
- ultrasound guided
- contrast enhanced ultrasound
- pain management
- computed tomography
- bone marrow
- single molecule
- drug release
- urinary tract