Login / Signup

The Duration of the Trial Influences the Effects of Mineral Deficiency and the Effective Phytase Dose in Broilers' Diets.

Mehran JavadiAlba CerisueloMaría Cambra-LópezJudit Macías-VidalAndrés DonadeuJavier DupuyLaura CarpinteroPablo FerrerJuan José Pascual Amorós
Published in: Animals : an open access journal from MDPI (2022)
Two trials varying in duration (short- and long-term) were conducted to evaluate the effects of providing deficient (NC) or sufficient (PC) Ca and P levels, and different doses of a new phytase (250, 500, and 1000 FTU/kg feed), in broiler feed on growth performance, nutrient digestibility and retention, and tibia mineralization. A total of 80 and 490 male chicks (Ross) of 21 and 1 days of age were used in the short- and long-term trials, respectively. In the long-term trial, chicks fed NC diets showed a lower ( p < 0.05) average daily gain and feed intake compared to chicks fed PC and a greater ( p < 0.05) feed conversion ratio compared to 500 and 1000 FTU/kg feed during the starting period. Regarding the effects on minerals' and nutrients' coefficients of retention, animals fed NC showed a significantly higher digestibility for P than those fed the PC diet in the long-term trial. Additionally, feeding 250 to 500 FTU/kg diets increased most of the nutrients' digestibility in the short-term but only P digestibility in the long-term trial. Tibia mineralization increased linearly with phytase addition ( p < 0.05) only in the long-term trial. In conclusion, the effects of dietary mineral and phytase levels on growth performance are more noticeable in young animals. In addition, the duration of the trial is key due to a possible adaptation phenomenon of birds to low P supplementary levels.
Keyphrases
  • phase iii
  • study protocol
  • phase ii
  • clinical trial
  • physical activity
  • randomized controlled trial
  • open label
  • heavy metals
  • body mass index
  • smoking cessation
  • middle aged
  • replacement therapy