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Patterns in the genome.

Wendy A Bickmore
Published in: Heredity (2019)
The human genome is not randomly organised, with respect to both the linear organisation of the DNA sequence along chromosomes and to the spatial organisation of chromosomes in the cell nucleus. Here I discuss how these patterns of sequence organisation were first discovered by molecular biologists and how they relate to the patterns revealed decades earlier by cytogeneticists and manifest as chromosome bands.
Keyphrases
  • single cell
  • endothelial cells
  • genome wide
  • single molecule
  • cell therapy
  • copy number
  • stem cells
  • induced pluripotent stem cells
  • cell free
  • amino acid
  • bone marrow
  • pluripotent stem cells
  • neural network