Albumin, filamin-A and cytokeratin 19 help distinguish intrahepatic cholangiocarcinoma from extrahepatic adenocarcinoma.
Yeon Seung ChungYoungsic JeonJeong Eun YooTaek ChungHyang Joo RyuHyunki KimHyungjin RheeYoung Nyun ParkPublished in: Hepatology international (2022)
Albumin ISH and IHC staining for filamin-A and CK19 showed distinct expression patterns between iCCA and extrahepatic adenocarcinomas from gallbladder, pancreas, and stomach. We developed iCCA-score that consisted of those three markers, and it showed better diagnostic performance than albumin ISH alone.