Different epidemiological profiles in patients with Zika and dengue infection in Tapachula, Chiapas in Mexico (2016-2018): an observational, prospective cohort study.

Pablo Francisco Belaunzarán-ZamudioHéctor Armando Rincón LeónSandra Caballero SosaEmilia RuizJosé Gabriel Nájera CancinoPaul Rodriguez de La RosaMaría de Lourdes Guerrero AlmeidaJohn H PowersJohn H BeigelSally HunsbergerKarina TrujilloPilar RamosFernando J Arteaga-CabelloAlexander López-RobleroRaydel Valdés-SalgadoHugo Arroyo-FigueroaEli BecerrilGuillermo Ruiz-Palaciosnull null

Published in: BMC infectious diseases (2021)

During the first 2 years of Zika introduction to this dengue hyper-endemic region, frequency of Zika peaked and fell over a two-year period; while dengue progressively increased with a predominance in 2018. Different epidemiologic patterns between Zika, dengue and UIE were observed. Trial registration Clinical.Trials.gov (NCT02831699).

Keyphrases

zika virus
aedes aegypti
dengue virus
clinical trial
phase ii
phase iii
randomized controlled trial
open label