Progestogen maintenance therapy for prolongation of pregnancy after an episode of preterm labour: A systematic review and meta-analysis.

Sofie H BreukingAnnemijn A De RuighFrederik J R HermansEwoud SchuitC Andrew CombsBegoña Martinez de TejadaMartijn A OudijkBen W MolEva Pajkrt

Published in: BJOG : an international journal of obstetrics and gynaecology (2023)

Progestogen maintenance therapy after PTL might have a modest effect on prolongation of latency time. When analysing low risk of bias studies only, this effect was not demonstrated. Validation through further research, preferably by an individual patient data meta-analysis is highly recommended.

Keyphrases

systematic review
preterm birth
machine learning
randomized controlled trial
case control
case report
electronic health record
meta analyses
pregnant women
gestational age