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PHOX2B is a reliable immunomarker in distinguishing peripheral neuroblastic tumours from CNS embryonal tumours.

Sanda AlexandrescuVera PaulsonAdrian DubucAzra LigonHart G Lidov
Published in: Histopathology (2018)
PHOX2B antibody is helpful in distinguishing between peripheral neuroblastic and CNS embryonal tumours, which are immunonegative, with the caveat that a subset of pineoblastomas has significant expression.
Keyphrases
  • blood brain barrier
  • poor prognosis
  • chemotherapy induced