Sex differences in susceptibility, severity, and outcomes of coronavirus disease 2019: Cross-sectional analysis from a diverse US metropolitan area.
Farhaan S VahidyAlan P PanHilda AhnstedtYashasvee MunshiHuimahn A ChoiYordanos TirunehKhurram NasirBita A KashJulia D AndrieniLouise D McCulloughPublished in: PloS one (2021)
In this analysis of a large US cohort, males were more likely to test positive for COVID-19. In hospitalized patients, males were more likely to have complications, require ICU admission and mechanical ventilation, and had higher mortality than females, independent of age. Sex disparities in COVID-19 vulnerability are present, and emphasize the importance of examining sex-disaggregated data to improve our understanding of the biological processes involved to potentially tailor treatment and risk stratify patients.
Keyphrases
- coronavirus disease
- mechanical ventilation
- intensive care unit
- sars cov
- cross sectional
- end stage renal disease
- acute respiratory distress syndrome
- respiratory syndrome coronavirus
- newly diagnosed
- chronic kidney disease
- emergency department
- risk factors
- climate change
- electronic health record
- cardiovascular events
- healthcare
- type diabetes
- peritoneal dialysis
- respiratory failure
- big data
- machine learning
- patient reported outcomes
- cardiovascular disease
- insulin resistance
- data analysis
- deep learning