Intra-arterial lidocaine therapy via the middle meningeal artery for migraine headache: Theory, current practice and future directions.

Marco Mancuso-Marcello Adnan I QureshiChristos NikolaIrina StoianYiFan JiaDanial SaeedPervinder Bhogal

Published in: Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences (2023)

Recent developments in neurointerventional research have seen the emergence of the middle meningeal artery (MMA) as an effective conduit for intra-arterial (IA) therapy for a number of pathologies. Here, we review the anatomical, pathophysiological and experimental basis for utilisation of the MMA for IA treatment of migraine headache. We explore the in-human case literature for the treatment of headaches with IA lidocaine and discuss considerations and challenges for future research.

Keyphrases

healthcare
endothelial cells
systematic review
current status
stem cells
mesenchymal stem cells
combination therapy
smoking cessation
pluripotent stem cells