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Efficacy and safety of difelikefalin in the treatment of hemodialysis patients with pruritus: A meta-analysis and systematic review.
Guifang Xue
Huaihong Yuan
Dandan Fan
Yujie Yang
Chunyan Ma
Jing Liu
Ruoxi Liao
Published in:
Clinical nephrology (2024)
Although difelikefalin can improve itching symptoms in HD patients, it can also increase adverse reactions based on the current literature. Therefore, more studies are needed to further explore the safety and efficacy of difelikefalin treatment.
Keyphrases
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systematic review
end stage renal disease
chronic kidney disease
peritoneal dialysis
newly diagnosed
ejection fraction
randomized controlled trial
meta analyses
combination therapy
depressive symptoms