Deprescribing in the Pharmacologic Management of Delirium: A Randomized Trial in the Intensive Care Unit.
Noll L CampbellAnthony J PerkinsBabar A KhanSujuan GaoMark O FarberSikandar KhanSophia WangMalaz A BoustaniPublished in: Journal of the American Geriatrics Society (2019)
When added to state-of-the-art clinical services, this deprescribing intervention had no impact on medication use in ICU participants. Given the age of the population, results of clinical outcomes may not be easily extrapolated to older adults. Nonetheless, improved approaches for deprescribing or preventing anticholinergics and benzodiazepines should be developed to determine the impact on delirium outcomes. J Am Geriatr Soc 67:695-702, 2019.