Defective expression of polarity protein Par3 promotes cervical tumorigenesis and metastasis.

J H ZhengS J JiaoL NaS Q ZhengZ H MaS W WangA AiliA Hasim

Published in: European journal of gynaecological oncology (2018)

The reduced Par3 expression in cervical cancer indicates tumor-suppressive properties of Par3 that may be a marker of poor prognosis in cervical cancer patients, and the molecular determinants of epithelial polarity which have tumorigenesis enhancing impact, might through EMT.

Keyphrases

poor prognosis
long non coding rna
epithelial mesenchymal transition
binding protein
single molecule
signaling pathway