Expression of angiopoietin-like protein 2 in ovarian tissue of rat polycystic ovarian syndrome model and its correlation study.

Dandan WangYihong GuoShujuan ChaiKe ShenYanchun LiRuiqin Zhao

Published in: Reproductive biology and endocrinology : RB&E (2020)

These findings suggest that ANGPTL2 might participate in the development of PCOS through the PI3K/Akt signaling pathway. Metformin improves IR by reducing the expression of ANGPTL2, thus improving the endocrine environment of PCOS and might change the disease outcome.

Keyphrases

poor prognosis
signaling pathway
polycystic ovary syndrome
binding protein
long non coding rna
pi k akt
type diabetes
case report
metabolic syndrome
skeletal muscle