Possible association between early formula and reduced risk of cow's milk allergy: The Japan Environment and Children's Study.
Junichiro TezukaMasafumi SanefujiTakahito NinomiyaTakahiro KawaharaHiroshi MatsuzakiYuri SonodaMasanobu OgawaMasayuki ShimonoReiko SugaSatoshi HonjoKoichi KusuharaShouichi Ohganull nullPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2020)
Regular exposure to formula milk at age 3 months or older is associated with lower CMA at 12 months old, suggesting that the effect of very early CM exposure on CMA may disappear if the exposure is brief. At present, however, the results of this observational study should not be used for formula recommendation and randomized controlled trials are required to confirm this association.