Genetic effects of sequence-conserved enhancer-like elements on human complex traits.

Xiang ZhuShining MaWing Hung Wong

Published in: Genome biology (2024)

Our findings provide a comprehensive assessment of how sequence-conserved enhancer-like elements affect complex traits in diverse tissues and demonstrate a generalizable strategy of integrating evolutionary and biochemical data to elucidate human disease genetics.

Keyphrases

genome wide
transcription factor
endothelial cells
induced pluripotent stem cells
gene expression
pluripotent stem cells
binding protein
dna methylation
electronic health record
amino acid