Prostate-Specific Membrane Antigen as Target for Neuroimaging of Central Nervous System Tumors.

Brittany M Stopa James Crowley Csaba Juhász Cara M Rogers Mark R Witcher Jackson W Kiser

Published in: Molecular imaging (2022)

There is a potential application for PSMA-targeted PET in neuro-oncology as a combination of diagnostic and therapeutic use, as a theranostic modality for managing CNS tumors. Further research is needed regarding the mechanism(s) of PSMA expression in CNS tumors and its differential performance by tumor type.

Keyphrases

pet ct
pet imaging
prostate cancer
blood brain barrier
poor prognosis
computed tomography
palliative care
positron emission tomography
photodynamic therapy
cancer therapy
climate change
binding protein
drug delivery
human health
cerebrospinal fluid
iron oxide