Effect of oral and transdermal oestrogen therapy on bone mineral density in functional hypothalamic amenorrhoea: a systematic review and meta-analysis.

Karoline AalbergKnut StavemFrode NorheimMichael Bjørn RussellAleksander Chaibi

Published in: BMJ open sport & exercise medicine (2021)

The literature suggests that TE might increase lumbar BMD in premenopausal women with FHA, but pooled results revealed no effect of the intervention. The findings do not support oestrogen therapy to improve BMD in these patient groups.

Keyphrases

bone mineral density
postmenopausal women
randomized controlled trial
systematic review
minimally invasive
clinical trial
single cell
stem cells
mesenchymal stem cells
smoking cessation
placebo controlled