Safety of non-steroidal anti-inflammatory drugs in postpartum period in women with hypertensive disorders of pregnancy: systematic review and meta-analysis.

Ioannis Bellos Vasilios PergialiotisA AntsaklisD LoutradisG Daskalakis

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)

This meta-analysis suggests that postpartum administration of NSAIDs is not associated with elevated blood pressure in women with hypertensive disorders of pregnancy. However, the existing evidence is of very low quality, thus future large-scale RCTs are warranted to verify the safety of postpartum NSAIDs in this population. Copyright © 2020 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

anti inflammatory drugs
blood pressure
systematic review
preterm birth
hypertensive patients
meta analyses
heart rate
pregnancy outcomes
randomized controlled trial
current status
pregnant women
skeletal muscle
insulin resistance