Does chemoradiotherapy benefit elderly patients with esophageal squamous cell cancer? A propensity-score matched analysis on multicenter data (3JECROG R-03A).
Mingqiu ChenXiaohong LiuChun HanXin WangYidian ZhaoQingsong PangXinchen SunGaofeng LiKaixian ZhangLing LiXueying QiaoYu LinJunqiang ChenZefen XiaoPublished in: BMC cancer (2020)
CRT with the current chemotherapy regimens may not improve the survival of elderly ESCC patients compared to RT-alone, except in patients with cT4 stage, cN0 stage or diabetes. However, due to the limitation of the retrospective nature of the current study, further clinical trials are required for confirmation.
Keyphrases
- squamous cell
- clinical trial
- end stage renal disease
- ejection fraction
- locally advanced
- type diabetes
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- rectal cancer
- cardiovascular disease
- prognostic factors
- papillary thyroid
- magnetic resonance imaging
- heart failure
- randomized controlled trial
- adipose tissue
- metabolic syndrome
- image quality
- patient reported outcomes
- magnetic resonance
- radiation therapy
- cardiac resynchronization therapy
- glycemic control
- weight loss
- skeletal muscle
- open label