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Current trends in targeted therapy for drug-resistant infections.

Leila RahbarniaSafar FarajniaBehrooz NaghiliVahideh AhmadzadehKamal VeisiRoghayyeh BaghbanSayna Toraby
Published in: Applied microbiology and biotechnology (2019)
Escalating antibiotic resistance is now a serious menace to global public health. It may be led to the emergence of "postantibiotic age" in which most of infections are untreatable. At present, there is an essential need to explore novel therapeutic strategies as a strong and sustainable pipeline to combat antibiotic-resistant infections. This review focuses on recent advances in this area including therapeutic antibodies, antimicrobial peptides, vaccines, gene therapy, genome editing, and phage therapy for tackling drug-resistant infections.
Keyphrases
  • drug resistant
  • multidrug resistant
  • acinetobacter baumannii
  • public health
  • genome editing
  • crispr cas
  • gene therapy
  • pseudomonas aeruginosa
  • data analysis